Inhaled Budesonide and Oral Dexamethasone Prevent Acute Mountain Sickness
نویسندگان
چکیده
منابع مشابه
Inhaled budesonide for acute mountain sickness.
In the present issue of the European Respiratory Journal, BERGER et al. [1] report the lack of efficacy of inhaled budesonide for the prevention of acute mountain sickness (AMS). This small well-designed study was undertaken to verify or refute the provocative finding of robust protection with budesonide against AMS reported by Chinese colleagues in 2014 [2] and 2015 [3]. In the presently repor...
متن کاملDexamethasone for prevention and treatment of acute mountain sickness.
We wished to determine in a field study the effectiveness of dexamethasone for prevention and treatment of acute mountain sickness (AMS). Prevention Trial: We transported 15 subjects from sea level to 4,400 m (PB = 400 mm Hg) on Denali (Mt. McKinley) by means of a 1-h helicopter flight. In a randomized, double-blind fashion we gave eight subjects a placebo and seven subjects 2 mg dexamethasone ...
متن کاملSuccessful treatment of acute mountain sickness with dexamethasone.
A double blind, randomised, placebo controlled trial of treatment with dexamethasone for acute mountain sickness was performed in the Capanna "Regina Margherita" at an altitude of 4559 m in the Alps Valais. After 12-16 hours of treatment (8 mg dexamethasone initially, followed by 4 mg every six hours) the mean acute mountain sickness score decreased significantly from 5.4 to 1.3, and eight of 1...
متن کاملCysteinyl leukotriene blockade does not prevent acute mountain sickness.
BACKGROUND Acute Mountain Sickness (AMS) is a multi-system disorder that is characterized by headache, anorexia, nausea, vomiting, insomnia, lassitude, and malaise. The syndrome is common in unacclimatized low altitude residents who rapidly ascend to terrestrial elevations exceeding 2,500 m. AMS may be a manifestation of hypoxia-induced cerebral edema resulting, in part, from increased capillar...
متن کاملOral antioxidant supplementation does not prevent acute mountain sickness: double blind, randomized placebo-controlled trial.
BACKGROUND Acute mountain sickness may be caused by cerebrovascular fluid leakage due to oxidative damage to the endothelium. This may be reduced by oral antioxidant supplementation. AIM To assess the effectiveness of antioxidant supplementation for the prevention of acute mountain sickness (AMS). DESIGN A parallel-group double blind, randomized placebo-controlled trial. METHODS The study...
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ژورنال
عنوان ژورنال: The American Journal of Medicine
سال: 2014
ISSN: 0002-9343
DOI: 10.1016/j.amjmed.2014.04.012